Estriol/Oestriol
Why has my veterinarian prescribed this medicine?
Oestriol is a natural oestrogen. Oestrogens tighten the bladder sphincter. Oestriol is used for the treatment of hormone-dependent urinary incontinence in spayed female dogs.
How does this medicine work?
Oestriol enhances the sensitivity of receptors in the smooth muscle of the bladder neck and urethra to sympathetic nerve stimulation.
How do I give this medication?
- This medication is given by mouth.
- Give this medication to your pet as directed by your veterinarian. READ THE LABEL CAREFULLY.
- Try to give this medication at about the same time each day. Some animals may only need treatment every second day.
- DO NOT give the pet more medicine than directed and DO NOT give the medicine more often than directed and for a longer period of time than directed.
- Try not to miss giving any doses.
What do I do if I miss giving a dose?
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give the pet two doses at once.
How do I store this medicine?
Keep this medicine out of reach of children. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
Potential side effects
- Although a drug has potential side effects, it does not mean that there is necessarily a high risk of any of these occurring. Tell your veterinarian if your pet has not been spayed.
- Side effects seen with this medication include swollen vulva, swollen mammary glands, vomiting, attractiveness to males, and vaginal bleeding. Contact your veterinarian if these side effects continue and are troublesome.
- Other side effects may occur. If you notice anything unusual, contact your veterinarian. Your veterinarian will need to re-check your pet regularly.
Possible drug interactions
- Make sure to tell your veterinarian what other medication you are giving to your pet.
- Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Jul 28, 2015.
