Milbemycin
Why has my veterinarian prescribed this medicine?
Milbemycin is used for control of internal parasites. Your veterinarian has prescribed this medication for the prevention of heartworm infection. Milbemycin kills immature stages of the parasite but not adult worms. If your pet has been travelling to and from heartworm risk areas, the animal must be examined by a veterinarian before commencing treatment with milbemycin.
Mosquitoes spread heartworm. Depending on the climate, your pet may need to be treated either all year round, or during and for one month before and after the insect season.
How does this medicine work?
Milbemycin interferes with parasite nerve transmission at the level of the post-synaptic membrane, resulting in paralysis and death.
How do I give this medication?
- This medication must be given with food, either mixed with food (rather than: the daily ration) or placed directly into the animal's mouth after feeding.
- Make sure each animal is fed individually and receives its whole dose.
- Give this medication to your pet as directed by your veterinarian. READ THE LABEL CAREFULLY.
- DO NOT give more medication than directed and DO NOT give more often than directed.
- Have a reminder system in place to indicate when the next dose should be given.
- Tell your veterinarian if you have more than one animal in the household.
- Wash your hands after handling the medication.
What if I miss giving a dose?
Give the dose as soon as possible and then resume a monthly dosage regimen. Do not give two doses at once.
How do I store this medicine?
- Keep this medicine out of reach and sight of children.
- Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight.
Potential side effects
- Side effects seen with this medication include pale mucous membranes, vomiting, laboured breathing, and excessive salivation.
- Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Possible drug interactions
- Make sure to tell your veterinarian what other medication you are giving to your pet.
- Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Created on Jul 31, 2015.
